Osseointegration in hip prostheses: experimental study in sheep

Sheep Hip Arthroplasty Model of Failed Implant Osseointegration.

Early secure stability of an implant is important for long-term survival. We examined whether micromotion of implants consistently would induce bone resorption and formation of a fibrous membrane and thereby prevent osseointegration. One micromotion implant was inserted into one of the medial femoral condyles in ten sheep. The micromotion device consists of an anchor bearing a PMMA implant and ...

Osseointegration of Zirconia (Y-TZP) Dental Implants: A Histologic, Histomorphometric and Removal Torque Study in the Hip of Sheep

Objectives: The purpose of the present study was to demonstrate the biocompatibility and rigid osseointegration of a zirconia (Y-TZP) dental implant with acid-etched surface. Materials and methods: Eight zirconia (Y-TZP) implants (CeraRoot, Barcelona) were inserted in the hip of an adult sheep. The animal was sacrificed after 2 months. Four implants were used for histology and histomorphometric...

Osseointegration and biocompatibility of different metal implants - a comparative experimental investigation in sheep

BACKGROUND In the present study, 4 different metallic implant materials, either partly coated or polished, were tested for their osseointegration and biocompatibility in a pelvic implantation model in sheep. METHODS Materials to be evaluated were: Cobalt-Chrome (CC), Cobalt-Chrome/Titanium coating (CCTC), Cobalt-Chrome/Zirconium/Titanium coating (CCZTC), Pure Titanium Standard (PTST), Steel, ...

An experimental animal model of aseptic loosening of hip prostheses in sheep to study early biochemical changes at the interface membrane

BACKGROUND Aseptic loosening of hip prosthesis as it occurs in clinical cases in human patients was attributed to wear particles of the implants, the response of the tissue dominated by macrophages and the production of inflammatory mediators and matrix degrading enzymes; however, the cascade of events initiating the process and their interaction regarding the time course is still open and disc...

Experimental Pathology of Ornithobilharzia turkestanicum in Sheep.